Table 1. IC₅₀ concentrations of respective drugs in respective derivatives of H1975 cells.

Drug	Class	H1975DM	H1975C5	H1975C6
BEZ235	PI3K/mTOR inhibitor	0.32 ± 0.13	2.29 ± 0.44*	1.94 ± 0.96*
GDC0941	PI3K inhibitor	25 ± 12	> 100	> 100
BYL719	PI3K inhibitor	6.0 ± 1.7	40 ± 25*	14 ± 2.5*
Ku0063794	mTOR inhibitor	0.64 ± 0.78	8.7 ± 0.51*	7.0 ± 1.5*
Gefitinib	EGFR inhibitor	> 10	> 10	> 10
PD98059	MEK inhibitor	> 10	> 10	> 10
AZD6244	MEK inhibitor	15 ± 1.8	19 ± 2.8	17 ± 3.1
Docetaxel	cytotoxic	< 0.001	< 0.001	< 0.001