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. 2017 Nov 24;8(66):110153–110165. doi: 10.18632/oncotarget.22656

Table 13. ALDH3B2 haplotype frequencies (%) in cases and controls and risk of ESCC.

Haplotypes Case (freq) Control (freq) Crude OR(95% CI) p
ALDH3B2Ars34589365Grs3741172Trs4646823Grs78402723Crs7947978Grs866907Grs9787887 247 (12.1) 323 (12.4) 1.007 [0.840∼1.206] 0.943
ALDH3B2Grs34589365Ars3741172Grs4646823Ars78402723Ars7947978Ars866907Grs9787887 184 (9.0) 219 (8.4) 1.106 [0.898∼1.363] 0.344
ALDH3B2Grs34589365Grs3741172Trs4646823Grs78402723Crs7947978Grs866907Ars9787887 1318 (64.6) 1735 (66.3) 1.000 1.000
ALDH3B2Grs34589365Grs3741172Trs4646823Grs78402723Crs7947978Grs866907Grs9787887 235 (11.5) 279 (10.6) 1.109 [0.919∼1.338] 0.281

Haplotypes were composited by ALDH3B2 rs34589365, rs3741172, rs4646823, rs78402723, rs7947978, rs866907, rs9787887. All those frequency < 3% were ignored in analysis, most common haplotype ALDH3B2Grs34589365Grs3741172 Trs4646823Grs78402723Crs7947978Grs866907Ars9787887 was selected as reference.