Table 9. MTHFR haplotype frequencies (%) in cases and controls and risk of NSCLC.
| Case (n = 1042) | Control (n = 2060) | Crude OR (95% CI) | P | |||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| G T G A C | 414 | 39.81 | 774 | 37.63 | 1.00 | |
| A T G A T | 317 | 30.48 | 687 | 33.40 | 0.86 (0.72–1.03) | 0.105 |
| G C A A T | 121 | 11.63 | 220 | 10.70 | 1.03 (0.80–1.32) | 0.828 |
| G T A G T | 92 | 8.85 | 185 | 8.99 | 0.93 (0.70–1.23) | 0.606 |
| G T G A T | 68 | 6.54 | 131 | 6.37 | 0.97 (0.71–1.33) | 0.853 |
| G T A A T | 13 | 1.25 | 21 | 1.02 | 1.16 (0.57–2.34) | 0.683 |
| Others | 15 | 1.44 | 39 | 1.90 | 0.72 (0.39–1.32) | 0.285 |
With the order of rs1801133 G>A, rs3753584 T>C, rs4845882 G>A, rs4846048 A>G and rs9651118 T>C in gene position.