Table 1.
Animal number | Unmodified meshes (CFU) | Drug-delivery meshes (CFU) |
---|---|---|
Control 1 | 200,334 | |
Control 2 | 84,875 | |
Control 3 | 84,004 | |
Control 4 | 567,362 | |
Experimental 1 | 300* | |
Experimental 2 | 300* | |
Experimental 3 | 300* | |
Experimental 4 | 300* | |
Experimental 5 | 300* | |
Experimental 6 | 300* | |
Average | 2.34×104 | 300* |
The four control animals receiving a standard, unmodified mesh showed extensive infection at the study end point (30 d), with an average of 2.34 × 104 CFU. The six experimental animals receiving antibiotic delivery meshes all showed no surviving bacteria. Even though no bacteria were detected, as per microbiological standards, all conditions are set at 300 CFU, which is the minimum detectable units for these experimental conditions.
Samples with 0 colonies were set to the minimum detectable unit of 300 CFU.