Table 3. Summary of microbiota composition characterized in the present study and comparison with that identified from fecal samples in recent studies.

		Present			Published
		APP/PS1a) (serum)			APP/PS1b) (fecal)	3xTg (fecal)
					(Harach et al., 2017)	(Bonfili et al., 2017)
<Microbial diversity>		WT vs. Tg			WT vs. Tg	WT vs. Tg
Alpha diversity		↑			↑	=

The microbiomes for which the percent composition increased or decreased by more than one z score in Tg-APP/PS1 are marked by ↑ and ↓, respectively. « and » denote infinite increases and decreases, respectively. The increases and decreases of the indicated microbiota in the previous studies are also marked by ↑ and ↓, respectively.

The z-score is expressed as X − µ/σ, where µ=mean; X=individual score; σ=standard deviation (SD). ^a)APPswe/PSEN1dE9; ^b)APPswe/PSEN1-L166P.