Fig. 3. Effect of calcium ascorbate on gastric juice volume and pH in the rat pylorus ligation-induced ulcer model.

After oral administration of distilled water (DW; as a control), ascorbic acid (105.96 mg/kg), or calcium ascorbate (135.24 mg/kg) to rats processed by pylorus ligation, the stomach was removed immediately following animal sacrifice and the gastric contents were collected at designated times. After the centrifugation of the gastric contents (1,800×g for 5 min), the volume (A) and pH (B) were measured. Data are expressed as the mean±SEM (n=5). ^**p<0.01, ^***p<0.001 vs. distilled water (DW); ^##p<0.01, ^###p<0.001 vs. ascorbic acid.