Skip to main content
. 2017 Dec 22;22(1):43–51. doi: 10.4196/kjpp.2018.22.1.43

Fig. 2. A CpG site is hypermethylated within the NAGA promoter in cisplatin-resistant cell lines.

Fig. 2

The DNA methylation status of CpG sites within the NAGA promoter region was quantified using the Illumina HumanMethylation 450 BeadChip in eight ovarian cancer cell lines. The Illumina HumanMethylation 450 BeadChip includes eleven CpG sites within NAGA promoter region, which is located at −656, −524, −498, −471, −299, −271, −260, −255, −157, +12 and +251 from TSS (A). The DNA methylation status of the CpG site located +251 relative to the TSS is illustrated in (B). The statistical differences between cisplatin-sensitive and -resistant cell lines were determined by a t-test. TSS, transcription start site.