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. 2017 Dec 22;22(1):43–51. doi: 10.4196/kjpp.2018.22.1.43

Fig. 3. NAGA mRNA expression is restored by demethylation in cisplatin-resistant cell lines.

Fig. 3

Eight ovarian cancer cell lines were treated with 5-aza-2′-deoxycytidine and NAGA mRNA expression was measured by RT-qPCR. The relative expression levels to dimethyl sulfoxide (DMSO)-treated controls in cisplatin-sensitive and cisplatin-resistant cell lines (A), or in eight individual cisplatin-resistant cell lines (B) are shown. Data are presented as the mean±SD from three independent experiments. Statistical analyses were performed using a t-test. Con, control; Aza, 5-aza-2′-deoxycytidine.