Figure 10.

Scheme for chemical evolution from simple molecules (astrophysical scenarios) to the systems chemistry complexity of proto-cellular systems (terrestrial scenarios) indicating their relationship with the chirality question. Adapted with the author's permission from [66]. On the right (green colour) the current hypothesis that the formation of primordial biopolymers requires enantiopure pools of building blocks. On the left (blue) the hypothesis presented here on the role of chirality during the different stages of chemical evolution: SMSB appears at the onset of polymer formation and replicator selection and, due to residual ee values coming from former simple asymmetric inductions or singular SMSB syntheses, the stochastic chiral sign distribution transforms into a deterministic final chiral sign.