Table 2. Results of univariate and multivariate Cox regression analyses for significant predictors of survival in gastric adenocarcinoma.
| Characteristics | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| HR (CI) | P | HR (CI) | P | ||
| Age | 1.021 (1.019–1.024) | <0.001 | 1.025 (1.023–1.026) | <0.001 | |
| Sex | |||||
| Male | Reference | Reference | |||
| Female | 0.911 (0.882–0.968) | <0.001 | 0.908 (0.880–0.937) | <0.001 | |
| Race | |||||
| White | Reference | ||||
| Black | 0.999 (0.994–1.061) | 0.152 | NS | NS | |
| Other | 0.990 (0.964–1.044) | 0.118 | NS | NS | |
| Charlson score | |||||
| 0 | Reference | Reference | |||
| 1 | 1.122 (1.091–1.163) | <0.001 | 1.083 (1.046–1.120) | <0.001 | |
| ≥2 | 1.455 (1.407–1.496) | <0.001 | 1.407 (1.340–1.478) | <0.001 | |
| Grade | |||||
| Well-differentiated | Reference | Reference | |||
| Moderately differentiated | 1.588 (1.439–1.766) | <0.001 | 1.304 (1.211–1.404) | <0.001 | |
| Poorly differentiated | 2.111 (1.883–2.241) | <0.001 | 1.624 (1.511–1.746) | <0.001 | |
| Tumor location | |||||
| Non-cardiac adenocarcinoma | Reference | Reference | |||
| Cardiac adenocarcinoma | 1.128 (1.100–1.151) | <0.001 | 1.396 (1.352–1.441) | <0.001 | |
| Chemotherapy | 0.859 (0.838–0.875) | <0.001 | 0.844 (0.809–0.880) | <0.001 | |
| Radiation | 0.931 (0.907–0.944) | <0.001 | 0.921 (0.844–0.960) | <0.001 | |
| No. of resected nodes | 0.989 (0.988–0.991) | <0.001 | 0.978 (0.977–0.980) | <0.001 | |
| Nodal stage | |||||
| N0 | Reference | Reference | |||
| N1 | 1.742 (1.678–1.808) | <0.001 | 1.896 (1.821–1.975) | <0.001 | |
| N2 | 2.379 (2.292–2.469) | <0.001 | 2.841 (2.724–2.963) | <0.001 | |
| N3 | 3.301 (3.181–3.426) | <0.001 | 4.511 (4.313–4.719) | <0.001 | |
HR = hazard ratio; CI = confidence interval; NS = not significant.