Table 4. Optimized Results after Ligand Screening for the Coupling of Different Fluorinated Protected Boronic Acids to 2,3,5,6-Tetrafluoroiodo-benzene.

^aReactions were performed with 1 equiv. 1 and the corresponding boronic acid and 2.2 equiv of Na₂CO₃ with 5 mol % Pd₂(dba)₃ and a 15 mol % of the corresponding ligand at 95 °C for 60 h on a 0.18 mmol scale.