Interactions among multiple N-BAR filaments.
Left are shown protein
configurations from CG MD simulations used to calculate the potential
of mean force, F, as a function of distance between
two filaments of interest, d, as displayed in the
plot on the right. In the center and bottom configurations, the black
line connects two filaments whose distance was kept constant throughout
the simulation. The colors in the plot match the colors in the protein
configurations. The black plot serves as a control of only two filaments.
All filaments contain six N-BARs. CG MD simulations were carried out
at ∼0.15 mN m–1. Maximum error per PMF calculation
(in kBT) for, respectively,
black, green, and blue plots is ±1.6, ± 1.1, and ±1.1.
The Boltzmann constant is kB, and T is the thermodynamic temperature.