Table 1.
Gal3 expression in biopsy specimens | |||||||||
---|---|---|---|---|---|---|---|---|---|
Marker | Gal3 epithelial | Gal3 epithelial + stroma | Ratio Gal3/CD68 epithelial | Ratio Gal3/CD68 epithelial + stroma | |||||
Median | SD | Median | SD | Median | SD | Median | SD | ||
T-Status | n | ||||||||
T1 | 8 | 103 | 72 | 101 | 80 | 0.43 | 0.23 | 0.19 | 0.17 |
T2 | 17 | 256 | 170 | 293 | 162 | 0.73 | 0.60 | 0.71 | 0.61 |
p-value | 0.032 | 0.024 | 0.045 | 0.018 | |||||
N-Status | n | ||||||||
N0 | 13 | 111 | 174 | 93 | 175 | 0.53 | 0.61 | 0.30 | 0.66 |
N+ | 12 | 290 | 133 | 276 | 125 | 0.73 | 0.49 | 0.68 | 0.47 |
p-value | 0.143 | 0.197 | 0.472 | 0.511 | |||||
L-Status | n | ||||||||
L0 | 18 | 115 | 132 | 110 | 126 | 0.55 | 0.41 | 0.31 | 0.40 |
L1 | 7 | 323 | 192 | 369 | 169 | 0.88 | 0.69 | 0.95 | 0.71 |
p-value | 0.054 | 0.013 | 0.020 | 0.008 | |||||
Pn-Status | n | ||||||||
Pn0 | 13 | 170 | 138 | 124 | 134 | 0.58 | 0.43 | 0.35 | 0.43 |
Pn1 | 9 | 256 | 185 | 344 | 178 | 0.73 | 0.68 | 0.66 | 0.71 |
p-value | 0.295 | 0.184 | 0.185 | 0.129 | |||||
Grading | n | ||||||||
G2 | 16 | 170 | 136 | 179 | 130 | 0.59 | 0.41 | 0.57 | 0.44 |
G3 | 6 | 337 | 188 | 369 | 177 | 1.00 | 0.75 | 1.09 | 0.79 |
p-value | 0.120 | 0.083 | 0.067 | 0.088 |
Table shows the Galectin 3 (Gal3) cell count (positive cells/mm2) and the ratio of Gal3 positive cells and CD68 positive cells in oscc biopsy specimens in view of histomorphologic parameters (T-, N-, L-, Pn-status, grading). Results for the epithelial tumor compartment and the whole analyzed area (epithelial + stroma) are given. Values represent the median, standard deviation (SD) and p-value (ANOVA)