Table 2.
Gal3 expression in tumor resection specimens | |||||||||
---|---|---|---|---|---|---|---|---|---|
Marker | Gal3 epithelial | Gal3 epithelial + stroma | Ratio Gal3/CD68 epithelial | Ratio Gal3/CD68 epithelial + stroma | |||||
Median | SD | Median | SD | Median | SD | Median | SD | ||
T-Status | n | ||||||||
T1 | 14 | 97 | 48 | 116 | 129 | 0.30 | 0.29 | 0.24 | 0.27 |
T2 | 20 | 241 | 127 | 302 | 169 | 0.73 | 0.79 | 0.58 | 0.64 |
p-value | 0.000 | 0.002 | 0.002 | 0.010 | |||||
N-Status | n | ||||||||
N0 | 19 | 126 | 89 | 169 | 164 | 0.71 | 0.71 | 0.42 | 0.50 |
N+ | 15 | 234 | 156 | 287 | 182 | 0.59 | 0.78 | 0.57 | 0.66 |
p-value | 0.030 | 0.106 | 0.943 | 0.337 | |||||
L-Status | n | ||||||||
L0 | 25 | 180 | 138 | 195 | 190 | 0.71 | 0.74 | 0.45 | 0.65 |
L1 | 9 | 203 | 115 | 223 | 143 | 0.59 | 0.74 | 0.46 | 0.26 |
p-value | 0.892 | 0.999 | 0.834 | 0.595 | |||||
Pn-Status | n | ||||||||
Pn0 | 21 | 130 | 134 | 191 | 206 | 0.48 | 0.68 | 0.42 | 0.67 |
Pn1 | 10 | 199 | 138 | 232 | 134 | 0.66 | 0.86 | 0.56 | 0.44 |
p-value | 0.452 | 0.959 | 0.942 | 0.679 | |||||
Grading | n | ||||||||
G2 | 26 | 155 | 132 | 194 | 169 | 0.52 | 0.46 | 0.45 | 0.44 |
G3 | 6 | 254 | 142 | 232 | 246 | 1.31 | 1.11 | 0.56 | 0.96 |
p-value | 0.422 | 0.528 | 0.008 | 0.183 |
Table shows the Galectin 3 (Gal3) cell count (positive cells/mm2) and the ratio of Gal3 positive cells and CD68 positive cells in oscc tumor resection specimens depending on histomorphologic parameters (T-, N-, L-, Pn-status, grading). Results for the epithelial tumor compartment and the whole analyzed area (epithelial + stroma) are given. Values represent the median, standard deviation (SD) and p-value (ANOVA)