Table 2.
LASSO regression analysis: factors associated with the risk of being a CFS/ME patient versus healthy controls
| Protiens that are positively associated with the risk of being a CFS/ME patient: | Proteins that are negatively associated with the risk of being a CFS/ME patient: | ||
|---|---|---|---|
| Protein | Weight | Protein | Weight |
| TWEAK | 5077 | BetaNGF | − 6683 |
| CCL4 | 4182 | LIFR | − 4053 |
| IL12B | 3898 | HGF | − 2153 |
| CDCP1 | 3611 | CXCL6 | − 1849 |
| VEGFA | 3138 | 4EBP1 | − 1317 |
| CSF1 | 2810 | SCF | − 1307 |
| IL10RB | 1737 | MMP1 | − 1256 |
| CCL11 | 1354 | ADA | − 1237 |
| CD5 | 1087 | CXCL10 | − 1223 |
| MCP1 | 1047 | IL18R1 | − 1076 |
| CASP8 | 0865 | CXCL9 | − 0697 |
| FGF5 | 0758 | CCL28 | − 0611 |
| IL6 | 0737 | CCL25 | − 0557 |
| CCL23 | 0591 | OSM | − 0544 |
| CX3CL1 | 0568 | CCL20 | − 0514 |
| ST1A1 | 0307 | CCL19 | − 0507 |
| TNFSF14 | 0303 | TRANCE | − 0498 |
| CD244 | 0302 | NT3 | − 0489 |
| IL10 | 0287 | MCP4 | − 0458 |
| CXCL5 | 0245 | TRAIL | − 0406 |
| LAPTGFbeta1 | 0166 | ENRAGE | − 0356 |
| OPG | 0107 | CD6 | − 0109 |
| TNFB | − 0062 | ||
| MMP10 | − 0033 | ||
| FGF23 | − 0017 | ||
| Optimism: 0.2652 AUC: 0.9996 Corrected AUC: 0.7344 | |||
Given associations are all conditional on the other predictors