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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Psychopharmacology (Berl). 2017 Sep 9;234(23-24):3455–3465. doi: 10.1007/s00213-017-4731-5

Figure 4.

Figure 4

Time-course of cocaine-like discriminative stimulus effects of PAL-329, l-methamphetamine, and PAL-169 in rhesus monkeys (n=4) trained to discriminate cocaine (0.4 mg/kg i.m.). Abscissae: Time after drug administration (min). Top ordinates: percentage cocaine-like responding for the entire session. Bottom ordinates: rate of responding expressed as responses/second. Other details as in Figure 2. Substitution data from two subjects were excluded from 5.6 mg/kg PAL-329 at 10–100 min and one subject for 3.2 mg/kg PAL-169 (30-min) and 18 mg/kg PAL-329 (100-min) because rate of responding was significantly suppressed (<0.2 responses/sec).