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Effects of pretreatment with d-amphetamine and d-methamphetamine on the discriminative stimulus effects of cocaine (0.032-0.32 mg/kg) in rhesus monkeys (n=4). Abscissae: Cumulative cocaine dose in mg/kg (log-scale), C = control injections of each drug dose from corresponding pretreatment times determined from time-course data. Top ordinates: percentage cocaine-like responding for the entire component. Bottom ordinates: rate of responding expressed as responses per second.
