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EGR3 binding to cytoskeletal-related promoters is altered by defeat. (a) Mice used for ChIP analysis showed significantly reduced time in the interaction zone following defeat (P<0.05, n = 6–10 pooled mice). (b) EGR3 displayed increase binding to the promoters of RhoA (P<0.05) and Actn1 (P<0.05) and decreased binding to the promoter of Shank2 (P<0.05). Exact statistics can be found in Supplementary Table 1.
