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. 2017;18(10):2717–2724. doi: 10.22034/APJCP.2017.18.10.2717

Table 2.

Genotypic Frequency of DNMT3B -149 among Lung Cancer Patients and Healthy Controls

Variables Cases Controls Unmatched Matched Adjusted
N=190 N=380 OR (95% CI)a OR (95% CI)b OR (95% CI)c
DNMT3B -149 genotypes
 TT 183 (96.3%) 345 (90.8%) 2.65 (1.16-6.09)d 2.65 (1.15-6.10)d 2.58 (0.98-6.78)f
 CT 7 (3.7%) 35 (9.2%) 1 1 1
 CC 0 (0.0%) 0 (0.0%)
 T allele 373 (98.2%) 725 (95.4%) 2.57 (1.13-5.85)d 2.24 (1.03-4.88)e 1.9 (0.84-4.28)
 C allele 7 (1.8%) 35 (4.6%) 1 1 1
a

Data were calculated by unconditional logistic regression;

b

Data were matched by age and gender, calculated by conditional logistic regression;

c

Matched data were calculated by conditional logistic regression and adjusted for pack-years of smoking, green tea consumption, exposure to cooking fumes, and family history of lung cancer;

d

P, 0.02;

e

P, 0.04;

f

P, 0.06.