Table 4.
The Joint Effects of Green Tea Consumption with DNMT3B -149 Genotypes for Lung Cancer Risk
| Variables | Drinking status | Drinking duration in years | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Drinkers | No drinkers | >10 | ≤0 | 0 | ||||||
| CA/CN | OR (95% CI)a | CA/CN | OR (95% CI)a | CA/CN | OR (95% CI)a | CA/CN | OR (95% CI)a | CA/CN | OR (95% CI)a | |
| DNMT3B -149 genotypes | ||||||||||
| TT | 42/121 | 2.33 (0.46-11.80) | 141/224 | 4.20 (0.85-20.87) | 19/58 | 1.06 (0.17-6.50) | 23/63 | 1.37 (0.23-8.32) | 141/224 | 2.17 (0.38-12.59) |
| CT | 2/9 | 1 | May-26 | 1.41 (0.21-9.37) | 2/5 | 1 | 0/4 | 0.52 (0.19-1.46) | 5/26 | 0.73 (0.10-5.54) |
| TT | 42/121 | 1.91 (0.38-9.51) | 141/224 | 2.84 (0.95-8.54) | 19/58 | 0.82 (0.14-4.78) | 23/63 | 2.48 (0.02-320.47) | 141/224 | 2.84 (0.95-8.54) |
| CT | 2/9 | 1 | 5/26 | 1 | 2/5 | 1 | 0/4 | 1 | 5/26 | 1 |
| Test for interaction | χ2=0.06 (1 df); P=0.81 | χ2=2.77 (2 df); P=0.25 | ||||||||
a
Data were matched by age and gender, calculated by (exact) conditional logistic regression and adjusted for pack-years smoked, exposure to cooking fume, and family history of lung cancer.