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. 2017 Dec 15;11(12):e0006138. doi: 10.1371/journal.pntd.0006138

Table 1. Cross-neutralization ability of FNAV against venoms from N. kaouthia, N. siamensis and O. hannah.

Venom Lethality FNAV
LD50a (μg/g) MLDb (μg/g) ED50 (μL/mouse) ER50 (mg/ml) Potencyc (mg/ml)
Naja kaouthia 0.34 (0.22–0.39) 0.471 ± 0.02 4.02 (1.27–5.43) 2.19 (1.16–6.91) 0.49
Naja siamensis 0.56 (0.35–0.62) 0.756 ± 0.05 18.33 (0.59–1.04) 0.85 (0.65–1.43) 0.23
Ophiophagus hannah 0.98 (0.75–1.08) 1.325 ± 0.08 NEd NE NE

a LD50: Median Lethal Dose—the dose of venom that induces lethality in 50% of subcutaneously injected mice (20–25 g). The values in parentheses are 95% confidence limits.

b MLD: Minimum Lethal Dose—the lowest dose of venom that induces lethality in 100% of subcutaneously injected mice.

c Potency: defined as the amount of venom in milligram was completely neutralized (100% protection) per milliliter of antivenom.

d NE: Display ineffective.