Table 2.
Effect of OJ on serum lipid profile in streptozotocin-induced diabetic rats at the end of treatment period.
| Parameters | Group-I (Normal control) | Group-II (Diabetic control) | Group-III (Metformin-treated) | Group-IV (OJ-treated) | Group-V (OJ-Metformin treated) |
|---|---|---|---|---|---|
| TC (mg/dl) | 90.71 ± 3.10 | 159.00 ± 7.56††† | 89.80 ± 3.15∗∗∗ | 105.01 ± 4.30∗∗ | 126.00 ± 7.70∗ |
| HDLc (mg/dl) | 40.90 ± 8.98 | 19.20 ± 3.89††† | 39.90 ± 7.74∗∗∗ | 41.70 ± 5.41∗∗∗ | 31.70 ± 4.56∗∗ |
| LDLc (mg/dl) | 30.04 ± 3.50 | 102.0 ± 6.34††† | 20.40 ± 4.59∗∗∗ | 44.70 ± 6.80∗∗ | 72.80 ± 5.60∗ |
| VLDLc (mg/dl) | 19.80 ± 2.50 | 37.80 ± 4.20††† | 29.50 ± 1.89∗∗ | 19.20 ± 2.05∗∗∗ | 21.50 ± 3.70∗∗∗ |
| TG (mg/dl) | 99.20 ± 12.50 | 189.00 ± 10.10††† | 148.00 ± 9.31∗∗ | 97.20 ± 10.20∗∗∗ | 108.00 ± 8.50∗∗∗ |
| Liver glycogen (mg/g) | 0.05 ± 0.001 | 0.02 ± 0.001††† | 0.04 ± 0.001∗∗∗ | 0.05 ± 0.002∗∗∗ | 0.06 ± 0.004∗∗∗ |
| Glycosylated hemoglobin (%) | 2.66 ± 0.40 | 8.36 ± 0.79††† | 3.56 ± 0.47∗∗∗ | 3.71 ± 0.55∗∗∗ | 3.96 ± 0.39∗∗∗ |
Values are expressed as mean ± SEM, n = 6, TC: total cholesterol; HDLc: high density lipoprotein cholesterol; LDLc: low density lipoprotein cholesterol; VLDLc: very low density lipoprotein-cholesterol; TG: triglycerides, †††p < 0.001 vs. normal control, ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001 vs. diabetic control. Values of diabetic control group were compared with normal control and those of drug-treated groups with diabetic control.