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. 2017 Dec 29;3(4):e191–e196. doi: 10.1055/s-0037-1615817

Table 1. Summary of papers found by literature search that meet the inclusion criteria.

Study author Type of study Total number of patients Surgery Follow-up time Comparison Aspirin dose Outcome measure
Raphael et al, 2014 15 Retrospective study 28,923 Total joint arthroplasty 90 d Aspirin vs. variable dose warfarin 325 mg BD Symptomatic VTE, complications, mortality.
Jiang et al, 2014 16 RCT 120 Total knee arthroplasty Unknown Aspirin vs. LMWH/ rivaroxaban Unknown Incidence of VTE
Zou et al, 2014 17 RCT 324 Total knee arthroplasty Unknown Aspirin vs. LMWH vs. rivaroxaban 100 mg/day Incidence of DVT, complications
Na et al, 2015 18 Retrospective study 328 Total knee arthroplasty 3 mo Aspirin vs. LMWH and aspirin 100 mg/d Incidence of DVT or PE, complications
Asopa et al, 2015 19 Retrospective study 9,035 Hip and knee arthroplasty 6 wk n/a 300 mg/d only given on discharge Incidence of symptomatic VTE
Pow and Vale, 2015 20 Retrospective study 402 Total hip and knee arthroplasty Unknown Aspirin vs. anticoagulants in hospital and discharge Unknown VTE prophylaxis prescribing, incidence of VTE
Ogonda et al, 2016 21 Retrospective study 11,459 Total hip, total knee, and unicompartmental knee arthroplasty 3 mo Aspirin vs. National Joint Registry rates 150 mg/d Incidence of DVT and PE, mortality
Yhim et al, 2017 22 Retrospective study 306,912 Total hip and knee arthroplasty 3 mo Aspirin vs. anticoagulants and no thromboprophylaxis Unknown Incidence of VTE, prescription rates

Abbreviations: BD, twice a day; DVT, deep vein thrombosis; LMWH, low molecular weight heparin; PE, pulmonary embolism; RCT, randomized control trial; VTE, venous thromboembolism.