Table 5.
Univariate analysis of predictors for treatment responses of intravenous methylprednisolone pulses
| Characteristics | Positive response group (n = 21) |
Negative response group (n = 32) |
P value |
|---|---|---|---|
| Age (year) | 58.9 ± 12.7 | 56.2 ± 12.4 | 0.450 |
| Female (n, %) | 16, 76.2 | 21, 65.6 | 0.544 |
| White blood cells (109/L) | 9.8 ± 4.8 | 8.3 ± 4.9 | 0.269 |
| Hemoglobin (g/L) | 73.7 ± 15.1 | 73.6 ± 11.7 | 0.984 |
| Platelet (109/L) | 236.0 ± 107.3 | 195.8 ± 67.6 | 0.137 |
| Serum albumin (g/L) | 30.9 ± 4.9 | 31.1 ± 5.1 | 0.889 |
| Serum globulin (g/L) | 31.6 ± 7.1 | 29.9 ± 3.3 | 0.333 |
| Alanine transaminase (u/L) | 13.8 ± 13.3 | 14.3 ± 7.6 | 0.866 |
| Serum creatinine (μmol/L) | 607.6 ± 142.1 | 701.2 ± 232.4 | 0.073 |
| eGFR (ml/min/1.73 m2) | 7.1 ± 2.0 | 6.7 ± 1.9 | 0.461 |
| UPCR (g/24 h) | 2.5 ± 0.7 | 3.4 ± 2.2 | 0.040 |
| ESR (mm/h) | 88.4 ± 43.3 | 87.9 ± 35.9 | 0.963 |
| CRP (mg/L) | 55.5 ± 55.6 | 36.5 ± 45.3 | 0.179 |
| MPO-ANCA postive (case, %) | 18, 85.7 | 29, 90.6 | 0.671 |
| PR3-ANCA postive (case, %) | 4, 19.0 | 3, 9.4 | 0.415 |
| Pulmonary involvement (case, %) | 16, 76.2 | 24, 75.0 | 1.000 |
| BVAS | 14.9 ± 3.1 | 15.4 ± 3.0 | 0.559 |
| Kidney length (cm) | 10.7 ± 1.0 | 10.6 ± 1.1 | 0.798 |
| Infections (case, %) | 9, 42.9 | 12, 37.5 | 0.778 |
eGFR Estimated glomerular filtration rate, UPCR Urine protein creatinine ratio, ESR Erythrocyte sedimentation rate, CRP C reactive protein, MPO Myeloperoxidase, PR3 Proteinase 3, BVAS Birmingham Vasculitis Activity Score