rGas6 decreased brain infarct ratio and improved neurological function after MCAO. (A, B) Representative images of TTC staining brain slices indicating brain infarction at 24 and 72 hours after MCAO. (C, F) Quantified infarct ratio and (D, G) neurological scores and (E, H) Beam walking score showed that rGas6 decreases infarction, neurological deficits and increases beam walking score in median dose at 24 hours and 72hours, high dose at 24hours after MCAO, * p<0.05 vs. Sham, # p<0.05 vs. MCAO + Vehicle, n=6 for each group; low dose of rGas6 had no beneficial effects on MCAO (p>0.05 vs. MCAO + Vehicle).