Table 1.

Effect of the solvent fractions of C. papaya fruit rind on parasitemia and survival of P. berghei infected mice on 4-day Peter's suppression test.

Treatment	Dose in mg/kg/day	% parasitemia	% chemosuppression	Survival date
Petroleum ether fraction	100	40.45 ± 2.1	23.03a3,b3,d2,e3	8.67 ± 0.52b3,e2
	200	34.48 ± 4.9	34.38a3,b3,c2,e3	8.83 ± 0.75b3,e2
	400	20.08 ± 2.4	61.78a3,b3,c3,d3	10.33 ± 1.03a3,c2,d2
Chloroform fraction	100	46.92 ± 4.7	10.72a1,b3,d2,e3	8.33 ± 0.52b3
	200	39.83 ± 3.3	24.20a3,b3,c2,e2	8.67 ± 0.82b3
	400	32.77 ± 1.61	37.65a3,b3,c3,d2	9.5 ± 1.05a2,b3
Methanol fraction	100	48.25 ± 4.38	8.18b3	7.67 ± 0.52b3
	200	43.53 ± 3.25	17.16a2,b3	8.50 ± 0.55b3
	400	42.88 ± 4.88	18.39a3,b3	8.17 ± 0.75b3
Vehicle	1 ml	52.55 ± 5.6	-	7.83 ± 0.75
Chloroquine	25	0	100a3,c3	30.00 ± 0.00a3

Data are expressed as mean ± SEM; n = 6; ^acompared to negative control (vehicle; 2% Tween 80), ^bcompared to chloroquine 25 mg/kg, ^ccompared to 100 mg/kg/day of the fraction, ^dcompared to 200 mg/kg/day of the fraction, and ^ecompared to 400 mg/kg/day of the fraction; ¹p < 0.05; ²p < 0.01; ³p < 0.001.