Table 2.

Effect of the solvent fractions of C. papaya root on parasitemia and survival of infected mice with P. berghei on 4-day Peter's suppression test.

Treatment	Dose mg/kg/day	% parasitemia	% chemosuppression	Survival date
Petroleum ether fraction	100	41.07 ± 2.55	21.85a3,b3,d1,e3	8.00 ± 0.63b3,e2
	200	35.98 ± 3.67	31.53a3,b3,c1,e2	9.17 ± 0.41a1,b3
	400	29.55 ± 4.42	43.77a3,b3,c3,d2	9.83 ± 1.33a3,b3,c2
Chloroform fraction	100	47.42 ± 1.94	9.77a2,b3,d3,e3	7.83 ± 0.41b3,e3
	200	39.28 ± 1.53	25.25a3,b3,c3,e3	8.83 ± 0.75b3,e2
	400	27.27 ± 3.36	48.11a3,b3,c3,d3	10.17 ± 0.75a3,b3,c3,d2
Methanol fraction	100	47.13 ± 4.39	10.31b3,e2	7.83 ± 0.75b3
	200	47.22 ± 4.97	10.15b3,e2	8.33 ± 1.03b3
	400	39.08 ± 2.76	25.63a3,b3,c2,d2	9.00 ± 0.89b3
Vehicle	1 ml	52.55 ± 5.6	-	7.83 ± 0.75
Chloroquine	25	0.00 ± 0.00	100	30.00 ± 0.00

Data are expressed as mean ± SEM; n = 6; ^acompared to negative control (vehicle; 2% Tween 80), ^bcompared to chloroquine 25 mg/kg, ^ccompared to 100 mg/kg/day of the fraction, ^dcompared to 200 mg/kg/day of the fraction, and ^ecompared to 400 mg/kg/day of the fraction; ¹p < 0.05; ²p < 0.01; ³p < 0.001.