Table 3.
Effect of the solvent fractions of Carica papaya rind on packed cell volume (PCV) of P. berghei infected mice on 4-day Peter's suppression test.
| Treatment group | Dose mg/kg/day | Packed cell volume | ||
|---|---|---|---|---|
| Day 0 | Day 4 | % change | ||
| Pet ether fraction | 100 | 57.7 ± 2.34 | 56.0 ± 2.83 | −3.02 |
| 200 | 58.2 ± 2.04 | 57.0 ± 1.67 | −2.09a1 | |
| 400 | 57.3 ± 2.42 | 57.2 ± 2.40 | −0.29a3 | |
|
| ||||
| Chloroform fraction | 100 | 56.3 ± 1.97 | 53.7 ± 2.94 | −5.09 |
| 200 | 56.3 ± 1.50 | 54.3 ± 2.94 | −3.85a1 | |
| 400 | 55.0 ± 1.09 | 54.7 ± 1.21 | −0.62a3 | |
|
| ||||
| Methanol fraction | 100 | 57.0 ± 1.09 | 55.7 ± 2.34 | −2.49 |
| 200 | 56.0 ± 1.79 | 56.0 ± 2.19 | −0.04 | |
| 400 | 56.3 ± 1.50 | 56.0 ± 2.83 | −0.70 | |
|
| ||||
| Vehicle | 1 ml | 56.0 ± 1.79 | 50.67 ± 3.26 | −10.79 |
|
| ||||
| Chloroquine | 25 | 57.0 ± 1.55 | 58.00 ± 2.10 | 1.69 |
Data are expressed as mean ± SEM; n = 6; acompared to negative control (vehicle; 2% Tween 80); 1p < 0.05; 3p < 0.001. Day 0 = pretreatment value on day 0. Day 4 = posttreatment value on day four.