Table 4.

Effect of the solvent fractions of Carica papaya rind on body temperature and weight of P. berghei infected mice on 4-day Peter's suppression test.

Treatment	Dose mg/kg	Temperature			Weight
		Day 0	Day 4	% change	Day 0	Day 4	% change
Pet ether fraction	100	37.1 ± 0.07	36.6 ± 0.33	−1.37a3	27.3 ± 1.03	26.3 ± 1.97	−4.15
	200	37.1 ± 0.13	36.9 ± 0.43	−0.64a3	22.0 ± 1.90	23.5 ± 1.22	6.41a3
	400	37.1 ± 0.07	36.9 ± 0.25	−0.41a3	26.0 ± 0.89	25.8 ± 1.17	−0.72a2
Chloroform fraction	100	37.2 ± 0.14	35.7 ± 0.29	−1.27a3	24.2 ± 2.14	23.5 ± 2.17	−3.01
	200	37.1 ± 0.12	37.0 ± 0.32	−0.36a3	26.5 ± 2.51	26.7 ± 3.20	0.30a2
	400	37.1 ± 0.08	36.9 ± 0.13	−0.41a3	24.7 ± 1.97	25.0 ± 1.55	1.23a2
Methanol fraction	100	37.1 ± 0.13	35.5 ± 0.34	−1.65a3	25.5 ± 1.05	24.2 ± 1.33	−5.66a1
	200	37.1 ± 0.15	35.7 ± 0.29	−1.09a3	23.8 ± 0.98	24.3 ± 1.21	1.91a3
	400	37.0 ± 0.08	35.6 ± 0.55	−1.29a3	24.5 ± 1.22	24.7 ± 1.21	0.62a3
Vehicle	1 ml	37.1 ± 0.14	34.05 ± 0.78	−5.89	25.33 ± 2.16	22.3 ± 2.25	−13.66
Chloroquine	25	37.1 ± 0.39	37.30 ± 0.32	0.41a3	33.3 ± 5.05	34.3 ± 5.35	3.16

Data are expressed as mean ± SEM; n = 6; ^acompared to negative control (vehicle; 2% Tween 80); ¹p < 0.05; ²p < 0.01; ³p < 0.001. Day 0 = pretreatment value on day 0. Day 4 = posttreatment value on day four.