Table 5.
Treatment group | Dose mg/kg/day | Packed cell volume | ||
---|---|---|---|---|
Day 0 | Day 4 | % change | ||
Petroleum ether fraction | 100 | 55.3 ± 2.94 | 53.5 ± 1.22 | −3.45 |
200 | 55.5 ± 1.52 | 54.3 ± 3.44 | −2.34a1 | |
400 | 56.3 ± 1.97 | 55.5 ± 1.52 | −1.51a3 | |
| ||||
Chloroform fraction | 100 | 55.7 ± 1.50 | 52.17 ± 2.23 | −6.81 |
200 | 55.0 ± 1.09 | 52.7 ± 1.63 | −4.47 | |
400 | 54.7 ± 1.03 | 53.5 ± 2.17 | −2.28a2 | |
| ||||
Methanol fraction | 100 | 56.0 ± 1.26 | 51.7 ± 1.50 | −8.41 |
200 | 55.0 ± 1.09 | 49.8 ± 2.23 | −10.50 | |
400 | 55.7 ± 1.50 | 54 ± 1.79 | −3.11 | |
| ||||
Vehicle | 1 ml | 56.0 ± 1.79 | 50.7 ± 3.27 | −10.79 |
| ||||
Chloroquine | 25 | 56.0 ± 1.55 | 56.0 ± 2.10 | 1.69 |
Data are expressed as mean ± SEM; n = 6; acompared to negative control (vehicle; 2% Tween 80); 1p < 0.05; 2p < 0.01; 3p < 0.001. Day 0 = pretreatment value on day 0. Day 4 = posttreatment value on day four.