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. Author manuscript; available in PMC: 2017 Dec 31.
Published in final edited form as: J Proteome Res. 2016 Sep 12;15(10):3624–3634. doi: 10.1021/acs.jproteome.6b00429

Table 1.

Clinicopathological Features of Cancer Cell Lines. Listed are the receptor regulation information (+, up regulation; −, down regulation) and the isolation location of each cell line. In this study, all cell lines were compared to MDA-MB-231BR since this cell line is a brain targeting breast cancer cell line.

Cell Line Estrogen Receptor Progesterone Receptor Human Epidermal Growth Factor Receptor 2 Location
MDA-MB-231BR − − − Subline of 231, brain targeting metastatic
MDA-MB-231 − − − Breast cancer cell line, non-specific metastatic derived from metastatic site: pleural effusion
HTB-126 − − − Breast cancer cell line, derived from a carcinoma
HTB-131 − − − Breast cancer cell line, derived from metastatic site: pericardial effusion
MDA-MB-361 + + + Breast cancer cell line, derived from metastatic site: brain
CRL-1620 N/A N/A N/A Brain cancer cell line