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| compound | R | KD (μM) | Soret peak shift (nm) | MIC (μg/mL) |
|---|---|---|---|---|
| 8a | H | 73.5 ± 0.7 | 416–422 | 50 |
| 8b | F | 35.6 ± 2.7 | 416–423 | 25 |
| 8c | Cl | 83.8 ± 7.4 | 416–421 | 25 |
| 8d | CH3 | 187 ± 13 | 416–418 | >100 |
| 8e | OCH3 | 96.5 ± 8.4 | 416–420 | 25 |
| 8f | Br | 193 ± 21 | 416–417.5 | 25 |
| 8g | I | no binding | 50 | |
| 8h | CN | no binding | >100 |
