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. 2017 Nov 29;60(24):10257–10267. doi: 10.1021/acs.jmedchem.7b01562

Table 3. KD and MIC Values for Series 13 Against M. tuberculosis H37Rv.

compound R KD (μM) Soret peak shift (nm) MIC (μg/mL)
13a H 394 ± 39 416–417.5 >100
13b F   no binding >100
13c Cl   no binding >100
13d CH3 290 ± 27 416–417.5 >100
13e OCH3 314 ± 43 416–418 100