Skip to main content
. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Arthritis Rheumatol. 2017 Oct;69(10):2062–2068. doi: 10.1002/art.40193

Figure 1. Association of serum adipsin levels with lcSSc and pulmonary arterial hypertension.

Figure 1

A. Serum levels of adipsin are not significantly different in patients than controls. B. Limited (lcSSc) patients have higher adipsin levels than controls (p=0.02) or diffuse (dcSSc) patients (p<0.0001) The blue dotted line represents the upper cutoff value for adipsin. Association of SSc groups stratified by limited/diffuse status and adipsin level with C. centromere, D. Scl70 antibodies, E. Pulmonary artery systolic pressure measured by echocardiography, F. Right heart catheterization-proven PAH. G. FVC/DLCO ratio H. DLCO I. TAPSE J. E' Lateral velocity. In panels C-H “dcSSc” group represents 82 patients with 81/82 having low adipsin, “lcSSc adipsin low” comprises 86 patients and “lcSSc adipsin high” represents 30 patients. Red bars indicate the mean ± 95% C.I. for each group. Mann-Whitney p-values are listed for each comparison. *p<0.01

Abbreviations. SSc = systemic sclerosis, lcSSc = limited cutaneous systemic sclerosis, dcSSc = diffuse cutaneous systemic sclerosis. PA = pulmonary artery. RHC = right heart catheterization. PAH = pulmonary arterial hypertension. FVC = forced vital capacity. DLCO = diffusion of lung carbon monoxide. TAPSE = tricuspid annular plane systolic excursion.