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. 2017 Oct 27;391(1):37–49. doi: 10.1007/s00210-017-1431-y

Fig. 1.

Fig. 1

Effects of EMD386088 and antidepressants given alone or in combination in the modified FST in rats. a Effects of EMD386088 and imipramine in the FST. b Effects of EMD386088 and reboxetine in the FST. c Effects of EMD386088 and moclobemide in the FST. d Effects of EMD386088 and bupropion in the FST. e Effects of EMD386088 and s-citalopram in the FST. EMD386088, imipramine, and s-citalopram were injected i.p. 30 min, while reboxetine, moclobemide, and bupropion were given i.p. 60 min before the test. Values represent the mean ± SEM and were analyzed by two-way ANOVA followed by Bonferroni’s post hoc test: *p < 0,05, **p < 0.01, ***p < 0.001relative to respective vehicle group; ###p < 0.001, ####p < 0.0001 relative to respective group receiving non-active dose of respective antidepressant drug without EMD386088, N = 6–8