TABLE 1.

Metabolic parameters of serum measured in WT and MT mice fed the SD or HFD

Parameters	Unit	SD		HFD
		WT	MT	WT	MT
Body weight	g	30.63 ± 0.61	29.85 ± 0.41	34.15 ± 0.96	37.40 ± 1.40a
Liver weight	g	1.58 ± 0.04	1.59 ± 0.04	1.65 ± 0.08	1.78 ± 0.07
Heart weight	g	0.13 ± 0.01	0.12 ± 0.01	0.14 ± 0.01	0.14 ± 0.01
Kidney weight	g	0.37 ± 0.01	0.36 ± 0.01	0.43 ± 0.02	0.43 ± 0.02
Glucose	mg/dl	179.52 ± 6.14	169.46 ± 18.69	168.92 ± 10.51	170.43 ± 10.66
Insulin	μU/ml	24.36 ± 3.25	25.11 ± 0.58	38.44 ± 7.87	33.88 ± 2.78
TGs	mg/dl	94.32 ± 7.10	101.47 ± 10.32	117.23 ± 14.89	106.39 ± 7.76
FFA	mEq/l	0.61 ± 0.05	0.71 ± 0.05b	0.66 ± 0.08	0.84 ± 0.08
β-Hydroxybutyrate	mmol/l	0.15 ± 0.01	0.16 ± 0.02	0.14 ± 0.01	0.14 ± 0.01
Chol	mg/dl	n.d.	n.d.	169.93 ± 18.02	174.09 ± 8.93
HDL-Chol	mg/dl	12.72 ± 0.43	12.98 ± 0.51	32.39 ± 2.82	32.81 ± 1.86
LDL-Chol	mg/dl	16.98 ± 1.29	15.06 ± 1.18	72.80 ± 12.68	89.81 ± 3.59

Body weight, liver weight, heart weight, kidney weight, serum glucose, insulin, TGs, FFA, β-hydroxybutyrate, Chol, HDL-Chol, LDL-Chol were measured from WT and MT mice fed the SD or HFD for 96 days. Data are shown as mean ± SEM (n = 6–7 per group). n.d., not detected.

^aP < 0.05, MT compared with WT mice fed HFD.

^bP < 0.05, MT compared with WT mice fed the SD.