Presentations of thyroid disorders after receiving immune checkpoint inhibition combination therapy or monotherapy. Thyroid disorders were divided into three groups: hypothyroidism only, thyrotoxicosis only, and thyrotoxicosis, followed by hypothyroidism. Percentage of patients with each thyroid disorder, calculated as the percentage of cases presenting with each thyroid disorder out of the total number of patients with thyroid disorders, represented for all patients (left, everyone), combination therapy (middle, combo), or monotherapy (right, mono) groups. Differences in initial presentation between the combination therapy and monotherapy groups were determined using the Fisher test; P = 0.01.