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. Author manuscript; available in PMC: 2018 Jan 2.
Published in final edited form as: Cancer Immunol Res. 2017 Oct 27;5(12):1133–1140. doi: 10.1158/2326-6066.CIR-17-0208

Table 2.

Demographic data of patients receiving anti–PD-1 monotherapy

Age, y Gender Malignancy Therapy TSH
Free T4
Free T3
TPO TSI
B Thyrotoxicosis Hypo B Thyrotoxicosis Hypo B Thyrotoxicosis Hypo
1 59 M Anal cancer Nivolumab 0.97 x 14.86 1.1 x 0.4 3.1 x 2 x x
2 66 F Breast ca. Pembrolizumab 5.82 x 17.38 0.9 x 0.5 x x x x x
3 67 F Breast ca. Pembrolizumab 1.46 0.02 30.46 1.1 3.1 <0.4 x x x x x
4 62 F Breast ca. Pembrolizumab 2.62 0.13 16.7 1.3 1.7 0.6 x x x x x
5 62 F Breast ca. Pembrolizumab 0.4 0.03 20.46 1.7 2.4 0.5 x x x x x
6 44 F Breast ca. Pembrolizumab 2.63 0.04 56.41 1 1.8 0.3 3.5 x x x x
7 42 F GBM of brain Nivolumab 1.55 0.09 31.62 1.1 2.3 <0.3 2.8 4.7 <1.4 x x
8 55 F Leiomyosarcoma Pembrolizumab 5.54 x 54.79 1.2 x 0.6 x x <1.4 73.6 x
9 50 F Leiomyosarcoma Pembrolizumab 2.57 x 58.93 1 x 0.4 x x x x x
10 49 M Melanoma Pembrolizumab 2.56 x 187.82 x x x x x x 20.7 x
11 77 F Melanoma Nivolumab 1.64 x 79.66 1 x 0.4 x x x 250.7 x
12 54 M Melanoma Pembrolizumab 1.15 0.01 x 1.4 2.5 x x x x x <1
13 55 F Melanoma Pembrolizumab 1.14 0.21 9.22 0.8 x 1.1 x x x x <1
14 73 F Melanoma Pembrolizumab 1.09 0.01 32.64 x x 0.4 x x x 149 x
15 72 M Melanoma Pembrolizumab 2.06 0.03 67.44 1 1.8 <0.3 2.2 x x 93.8 <1
16 55 F Melanoma Pembrolizumab 2.66 x 56.78 x x <0.3 x x x x x
17 41 F Melanoma Pembrolizumab 0.49 0.03 x x 2.7 x x 5.9 x x x
18 55 F Melanoma Nivolumab 1.37 x 21.82 x x x x x x x x

Abbreviations: M, male; F, female; B, baseline; hypo, hypothyroidism; GBM, glioblastoma; TSH, thyroid stimulating hormone; free T4, free thyroxine; free T3, free triiodothyronine.