Table 1.
Protection efficacy in different groups of chickens against vvIBDV challenge.
Sl. No | Groups | a Mortality | b B/B Ratio | c Bursal Lesion Score | d Protection Percentage |
---|---|---|---|---|---|
1 | Unvaccinated unchallenged | - | 0.67 ± 0.28 | 0 ± 0 | - |
2 | Unvaccinated challenged | 10/10 (100%) | 0.24 ±0.09 | 4.6 ± 0.2 | 0/10 (0%) |
3 | Live IBDV vaccine | 0/10 (0%) | 0.48 ± 0.01 | 2.2 ± 0.2 | 10/10 (100%) |
4 | Inactivated IBDV killed vaccine | 1/10 (10%) | 0.43 ± 0.02 | 2.8 ± 0.2 | 9/10 (90%) |
5 | rNDV F/VP2 | 0/10 (0%) | 0.54 ±0.02 | 2.0 ± 0.2 | 10/10 (100%) |
a Mortality was recorded during 10 days period after virus challenge and presented as number of dead chickens/total number of chickens in each group and percentage in parenthesis. b Bursa/Body weight ratios was calculated by bursal weight divided by body weight × 100 and presented as the mean ± standard deviation from each group. c Bursal lesion score was measured from 0 to 4 based on the increasing severity of bursal lesions; (0) no lesions, (1) mild scattered cell depletion in a few follicles, (2) moderate with 1/3–1/2 of the follicles atrophied or with depleted cells, (3) diffuse with atrophy in all follicles, (4) acute inflammation and necrosis typical of IBD and expressed as the mean ± standard deviation from each group. d Protection percentage was determined as the number of protected chickens/total number of chickens in a group ×100.