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. 2017 Oct 24;10(4):83. doi: 10.3390/ph10040083

Figure 3.

Figure 3

IL-4 treatment reduces the number of iNOS-expressing cells in the injured spinal cord. Distribution of iNOS+ cells along the rostrocaudal axis of the spinal cord (A); Quantification of iNOS+ cells in the whole spinal cord revealed a significant reduction of iNOS-producing cells in IL-4-treated rats (B); A significant reduction of iNOS-expressing cells was also observed in the rostral (E) area of the spinal cord but not at the epicenter (F) and in the caudal (H) regions. Schematic and low-magnification photomicrograph indicating areas where the analyses were performed (dashed lines) (C); Representative images of positive staining for iNOS+ cells of saline (D) and IL-4 treated (H) group. Values shown as mean ± SEM. * p < 0.05; ** p <0.01. Scale bar = 100 µm.