Table 1.
Baseline demographic and clinical details for all participants randomized to intervention.
| Standard Diet Group | HPHFib Group | |
|---|---|---|
| n | 39 | 44 |
| Age (years) 1 | 39 (18–65) | 44 (21–61) |
| Body Mass Index (BMI) (kg/m2) 2 | 32.3 (5.1) | 32.9 (5.5) |
| Weight (kg) 2 | 89.1 (14.3) | 87.8 (16.0) |
| Systolic blood pressure (mm Hg) 2 | 120 (14) | 119 (14) |
| Diastolic blood pressure (mm Hg) 2 | 78 (8) | 78 (8) |
| Glucose status | ||
| Normal | 36 (92.3) | 38 (86.4) |
| Impaired glucose tolerance | 2 (5.1) | 6 (13.6) |
| Diabetes | 1 (2.6) | |
| Menstrual Status | ||
| Premenopausal | 22 (56.4) | 26 (59.1) |
| Post-menopausal | 16 (41.0) | 12 (27.3) |
| Hysterectomy | 1 (2.6) | 6 (13.6) |
| Smoking history | ||
| Never smoked | 24 (61.5) | 31 (70.5) |
| Former smoker | 15 (38.5) | 11 (25.0) |
| Current smoker | 0 | 2 (4.5) |
| On metformin | 2 (5.1) | 2 (4.5) |
| On lipid lowering medications | 3 (7.7) | 3 (6.8) |
| On blood pressure medications | 4 (10.3 | 4 (9.1) |
| Insulin resistance 3 | 13 (33.3) | 23 (52.3) |
| DISST Insulin resistance 4 | 31% | 28% |
1 mean (range); 2 mean (SD); all other values are n (%); 3 defined by the McAuley method where Gffm/I ≤ 6.3 G/mU/l; 4 ISIclamp equivalent < 1.0 e−2mg/kg/(pmol/L)/min—Only calculated for participants for whom Dynamic Insulin Sensitivity and Secretion Test (DISST) data was also available at week 4 or week 10 (n = 35 for StdD and n = 39 for the relatively high protein, high fibre diet (HPHFib)).