Table 1.

Voxel-based morphometry comparison between pigs provided LOW and MOD dietary sialyllactose ¹.

			Cluster	Peak Level		Local Maxima Coordinates 3
Tissue	Comparison	Anatomic Region 2	(# Voxels)	p-Value	Pseudo-t	x	y	z
Grey	LOW > MOD	Lateral Ventricle/Corpus Callosum	141	<0.001	5.03	−4.9	14.0	7.0
		Right Cortex	1160	<0.001	4.5	9.1	10.5	−5.6
		Midbrain		0.001	4.02	−3.5	4.2	−9.8
		Midbrain/Right Cortex		0.007	2.8	7.7	2.8	−9.8
		Right Cortex	28	0.004	3.15	7.0	26.6	−2.8
		Left Cortex	163	0.004	3.13	−18.2	4.2	−2.1
	MOD > LOW	Left Cortex	139	<0.001	5.01	−14.7	4.2	11.9
		Right Cortex	39	0.001	3.74	12.6	0.7	11.9
		Left Cortex	23	0.004	3.1	−6.3	3.5	18.9
White	LOW > MOD	Caudate	128	0.001	3.95	2.1	18.9	2.8
		Midbrain/Right Cortex	93	0.001	3.74	7.7	3.5	−9.1
	MOD > LOW	Pons	147	<0.001	4.33	−6.3	−9.8	−9.1
		Left Cortex	32	0.007	2.85	−16.1	4.9	11.9
		Left Cortex	30	0.007	2.8	−12.6	0.7	12.6

¹ Voxel-based morphometry analysis of grey and white matter differences in the LOW (n = 9) and MOD (n = 7) pig brains. A threshold of p < 0.01 and minimum cluster size of 20 voxels was used to determine uncorrected p-values listed in the table. ² Brain regions based on estimates from the University of Illinois Pig Brain Atlas [14]. ³ Local Maxima Coordinates: X increases from left (−) to right (+), y increases from posterior (−) to anterior (+) and z increases from inferior (−) to superior (+). Abbreviations: # (number of voxels).