Table 3.

Apparent permeability coefficients (P_app) of flavonoids in Caco-2 monolayer.

No.	Papp A to B × 10−6 cm/s	Papp B to A × 10−6 cm/s	Ratiop	No.	Papp A to B × 10−6 cm/s	Papp B to A × 10−6 cm/s	Ratiop
1	22.35 ± 1.37	21.73 ± 1.21	0.97	16	4.24 ± 1.25	5.96 ± 1.20	1.41
2	21.86 ± 0.585	23.94 ± 0.45	1.10	17	4.04 ± 0.07	4.28 ± 0.44	1.06
3	16.43 ± 1.20	18.07 ± 1.62	1.10	18	23.50 ± 0.85	27.92 ± 2.76	1.19
4	1.95 ± 0.53	0.71 ± 0.21	0.37	19	32.13 ± 2.98	35.34 ± 1.16	1.10
5	10.10 ± 7.33	21.45 ± 2.12	2.12	20	3.73 ± 0.73	5.09 ± 1.55	1.36
6	17.12 ± 1.72	16.92 ± 1.02	0.99	21	30.97 ± 0.80	36.96 ± 1.97	1.19
7	6.78 ± 0.12	8.41 ± 0.62	1.24	22	6.32 ± 1.16	26.08 ± 2.08	4.13
8	3.28 ± 0.32	2.81 ± 0.24	0.86	23	17.42 ± 1.78	18.31 ± 1.83	1.05
9	1.94 ± 0.41	1.75 ± 0.44	0.90	24	2.25 ± 0.96	2.70 ± 0.41	1.20
10	2.55 ± 1.45	4.68 ± 0.41	1.84	25	12.45 ± 0.91	6.23 ± 0.46	0.50
11	8.23 ± 0.87	21.58 ± 0.32	2.62	26	33.90 ± 3.55	42.19 ± 3.11	1.24
12	6.68 ± 0.93	5.92 ± 0.45	0.89	27	31.07 ± 2.13	30.48 ± 2.13	0.98
13	0.35 ± 0.06	0.23 ± 0.03	0.66	28	11.11 ± 0.51	10.70 ± 2.98	0.96
14	0.29 ± 0.01	0.44 ± 0.01	1.50	29	13.76 ± 0.73	20.04 ± 1.29	1.46
15	1.09 ± 0.02	0.90 ± 0.42	0.83	30	4.25 ± 0.53	5.08 ± 1.08	1.20

P_{app A to B}: Transport of a flavonoid from apical to basolateral side; P_{app B to A}: Transport of a flavonoid from basolateral to apical side; Ratio_P: the ratio of P_{app B to A} to P_{app A to B}. Data are means ± SD (n = 3–6). P_app value of Lucifer yellow carbohydrazide (CH) was about (3.58 ± 0.12) × 10⁻⁷ cm/s. The incubation time was 60 min.