Figure 6.

The in vivo safety of topically applied flavonoids on skin after a 7-day exposure: (A) ΔTEWL-time curves; (B) the histology of sham control skin; (C) the histology of aqueous medium-treated skin; (D) the histology of myricetin-treated skin; (E) the histology of naringenin-treated skin; (F) the histology of quercetin-treated skin; (G) the histology of kaempferol-treated skin; (H) the histology of baicalein-treated skin; (I) the histology of naringin-treated skin; (J) the histology of rutin-treated skin; and (K) the histology of baicalin-treated skin. The TEWL data are presented as the mean of six experiments ± S.D.