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. 2017 Nov 30;9(12):1305. doi: 10.3390/nu9121305

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Doses of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and total omega-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) from randomised controlled trials on n-3 LCPUFA supplementation and clinical cardiovascular disease (CVD) outcomes. The red line shows that a DHA dose of 500 mg or greater results in significant CVD outcomes. * Significant effects (p < 0.05); ^# only 140 per group showing a trend towards a significant effect (p = 0.063). Sign means significant and n.s. means not significant.