Table 2.

Distribution of resveratrol-3-O-glucuronide in plasma (nmol/mL), various organs (nmol/g of tissue), urine (nmol/mL), and feces (nmol/g wet content) in mice at different time-points following the intragastric administration of resveratrol at a single dose of 10 mg/kg. Maximum concentrations (C_max values) are in bold.

Sample	Resveratrol-3-O-Glucuronide Concentration
	0.5 h	1 h	1.5 h	2 h	4 h	6 h	8 h
Plasma	0.289 ± 0.102	0.081 ± 0.055	0.082 ± 0.040	0.076 ± 0.021	0.037 ± 0.019	0.090 ± 0.045	0.016 ± 0.011
Spleen	0.785 ± 1.360	1.908 ± 1.305	1.767 ± 1.061	ND	ND	ND	ND
Liver	2.173 ± 1.120	0.758 ± 0.488	0.984 ± 0.333	0.821 ± 0.380	0.480 ± 0.201	0.059 ± 0.101	0.057 ± 0.056
Kidney	2.665 ± 2.066	2.119 ± 1.598	1.556 ± 0.702	1.749 ± 0.759	0.351 ± 0.377	0.329 ± 0.048	0.202 ± 0.190
Heart	2.155 ± 1.284	0.370 ± 0.640	0.230 ± 0.398	0.269 ± 0.467	0.198 ± 0.114	0.145 ± 0.112	ND
Lung	6.440 ± 2.566	1.179 ± 0.658	1.527 ± 0.781	2.459 ± 0.471	0.185 ± 0.120	0.124 ± 0.095	ND
Stomach	72.69 ± 41.68	35.83 ± 10.97	21.93 ± 7.397	8.483 ± 3.440	2.754 ± 1.625	0.898 ± 0.786	1.140 ± 1.396
Duodenum	46.03 ± 36.63	15.96 ± 11.51	26.49 ± 13.38	3.761 ± 0.734	1.553 ± 1.101	0.672 ± 0.599	0.445 ± 0.241
Jejunum	11.30 ± 7.849	3.658 ± 2.922	10.74 ± 2.962	2.610 ± 2.396	0.946 ± 0.508	0.291 ± 0.234	0.183 ± 0.060
Ileum	35.07 ± 7.835	118.6 ± 49.70	12.26 ± 0.822	3.282 ± 2.030	1.716 ± 0.814	0.492 ± 0.440	0.594 ± 0.328
Cecum	1.528 ± 1.299	0.702 ± 0.653	0.627 ± 1.085	3.167 ± 2.962	ND	ND	ND
Colon	1.845 ± 0.530	0.707 ± 0.540	4.385 ± 5.582	3.830 ± 3.202	0.805 ± 0.394	ND	ND
Thymus	12.39 ± 2.539	ND	ND	ND	ND	ND	ND
Muscle	0.683 ± 0.673	0.642 ± 0.090	0.622 ± 0.299	0.342 ± 0.309	0.232 ± 0.101	ND	ND
Brain	ND	ND	ND	ND	ND	ND	ND
Urine	362.7 ± 86.98	522.5 ± 289.7	440.1 ± 146.9	147.5 ± 78.32	168.1 ± 118.9	120.5 ± 51.62	96.92 ± 36.83
Feces	22.60 ± 9.050	ND	ND	ND	ND	1.524 ± 1.321	9.743 ± 1.216

Data are expressed as the mean ± SD; n = 3. ND: not detected.