Table 3.
Effects of streptozotocin (STZ) and Spirulina (Spi) extract on body weight; levels blood glucose, cholesterol, TG, BUN, creatinine.
| Initial Weight (g) | Final Weight (g) | Glucose (mg/dL) | Total Cholesterol (mg/dL) | TG (mg/dL) | BUN (mg/dL) | Creatinine (mg/dL) | |
|---|---|---|---|---|---|---|---|
| Control | 230.0 ± 5.32 | 346.6 ± 4.21 | 2.00.5 ± 15.3 | 81.0 ± 1.47 | 54 ± 6.9 | 20.6 ± 1.0 | 0.5 ± 0.01 |
| Spi | 235.0 ± 4.20 | 353.0 ± 3.65 | 252 ± 16.1 | 77.0 ± 1.05 | 48.0 ± 5.9 | 20.7 ± 0.4 | 0.6 ± 0.02 |
| STZ (2 weeks) | 235.0 ± 5.44 | 284.0 ± 7.55 | 522.3 ± 4.36 | 125.5 ± 3.24 | 414.0 ± 37.28 | 38.8 ± 2.05 | 0.5 ± 0.02 |
| Spi + STZ | 230.0 ± 6.03 | 295.3 ± 7.35 | 469.7 ± 19.93 | 108.0 ± 2.22 | 360.0 ± 14.71 | 31.1 ± 1.10 | 0.5 ± 0.02 |
| STZ (4 weeks) | 260.0 ± 2.56 | 234.8 ± 13.01 | 639 ± 7.8 | 129.3 ± 5.31 | 232 ± 34.2 | 43.7 ± 3.0 | 0.5 ± 0.02 |
| STZ + Spi | 260.0 ± 5.13 | 284.0 ± 6.97 a | 574 ± 16.7 a | 105.3 ± 1.83 a | 126.8 ± 11.1 a | 39.9 ± 2.0 | 0.5 ± 0.02 |
Values are expressed as means ± SEM for six animals in each group. a p < 0.05, significant difference between the STZ (4 weeks)-treated and the Spi extract-pretreated group (Spi + STZ).