Table 1.
Drugs Currently Approved for the Treatment of Type 1 Diabetes.
| Compound | Date First Approved | Comments |
|---|---|---|
| Regular human insulin | 1982 (FDA), 1984 (Europe); Bovine insulin: 1922 | Peak insulin levels 2-4 hours after injection |
| NPH insulin | Marketed 1950 | Long acting insulin |
| Insulin aspart | 1999 (EMA), 2000 (FDA) | Rapid acting insulin analogue |
| Insulin lispro | 1996 (EMA), 1996 (FDA) | Rapid acting insulin analogue |
| Insulin glulisine | 2004 (EMA), 2004 (FDA) | Rapid acting insulin analogue |
| Insulin glargine | 2000 (EMA), 2000 (FDA) | Long acting insulin analogue |
| Insulin detemir | 2004 (EMA), 2005 (FDA) | Long acting insulin analogue |
| Insulin degludec | 2013 (EMA) 2015 (FDA) |
Long acting insulin analogue |
| Insulin glargine U300 | 2015 (EMA), 2015 (FDA) | Long acting insulin analogue |
| Afrezza® inhaled insulin | 2014 (FDA) | Rapid acting insulin for inhalation |
| Pramlintide | 2005 (FDA) | Amylin analogue |