Table 2.

Bivariate and multivariable logistic regression model of variables associated with receipt of ≥1 parenteral antimicrobial dose among patients receiving outpatient chronic hemodialysis

	Bivariate analysis			Multivariable analysis
Variable	OR	95% CI	P value	OR	95% CI	P value
Age, each additional year	1.00	0.98–1.01	.82
Male sex	0.58	0.35–0.97	.04
Race-ethnicity
White	ref	—	—	ref	—	—
Black	1.31	0.75–2.31	.35
Other	2.15	1.04–4.42	.04	2.72	1.18–6.25	.02
Primary indication for hemodialysis, diabetes mellitus (vs other)	1.25	0.75–2.07	.39
Tunneled catheter for access (vs arteriovenous access)	3.33	1.95–5.66	<.001	5.76	2.97–11.15	<.001
Unit B	1.33	0.80–2.22	.27
Daytime shift (vs evening shift)	3.39	0.98–11.73	.05	4.80	1.26–18.25	.02
Duration of study participation, each additional month	1.16	1.08–1.26	<.001	1.26	1.15–1.39	<.001
Duration of hemodialysis at time of enrollment, each additional year	1.04	0.96–1.12	.36
Charlson Comorbidity Index score >4	1.83	1.10–3.05	.02
Requires wheelchair or bedbound	2.00	0.99–4.03	.05
Chronic wound present on enrollment	1.98	0.74–5.30	.18
Immunosuppressive medication at time of enrollment*	2.11	0.92–4.83	.08
History of prior organ transplant	1.07	0.41–2.74	.89
Malignancy	1.29	0.46–3.68	.63
History of ≥1 multidrug-resistant organism in 12 mo preceding enrollment	4.22	1.70–10.49	.002	5.85	1.96–17.45	.002
Hospitalizations in the 12 mo prior to enrollment			.09
No hospitalizations	ref	—	—
1–2 hospitalizations	1.51	0.79–2.90	.21
≥3 hospitalizations	2.15	1.07–4.29	.03

CI, confidence interval; OR, odds ratio; ref, reference.

^*Immunosuppressive medications include corticosteroids (prednisone dose equivalent of ≥20 mg/d), immunomodulators, and cancer chemotherapeutic treatment.