Table 2.
Proportional hazards models estimating the risk of renal function events in the propensity score–matched cohorts after kidney cancer surgery
| Characteristic | Preoperative Kidney Function eGFR>30 ml/min per 1.73 m2 | Preoperative Kidney Function eGFR>60 ml/min per 1.73 m2 | ||
|---|---|---|---|---|
| Unadjusted HR (95% CI) | Adjusted HR (95% CI) | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | |
| Age (per 10 yr increase) | 1.69 (1.47 to 1.94)a | 1.18 (1.02 to 1.38)a | 1.60 (1.40 to 1.82)a | 1.64 (1.43 to 1.89)a |
| Sex (female versus male) | 0.56 (0.08 to 4.0) | 2.13 (0.29 to 15.5) | 0.59 (0.08 to 4.23) | 6.62 (0.9 to 48.6) |
| Race/ethnicity | ||||
| Black versus white | 1.07 (0.76 to 1.52) | 0.71 (0.5 to 1.02) | 0.85 (0.63 to 1.16) | 0.36 (0.26 to 0.51)a |
| Other/unknown versus white | 1.44 (0.88 to 2.35) | 1.41 (0.86 to 2.32) | 0.67 (0.37 to 1.23) | 0.75 (0.41 to 1.37) |
| Serum creatinine (per 0.1 mg/dl increase) | 1.40 (1.35 to 1.45)a | 1.40 (1.35 to 1.45)a | 1.55 (1.44 to 1.66)a | 1.90 (1.74 to 2.08)a |
| Partial versus radical nephrectomy | 0.37 (0.28 to 0.47)a | 0.34 (0.26 to 0.43)a | 0.16 (0.12 to 0.21)a | 0.15 (0.11 to 0.19)a |
| Charlson score | ||||
| 1 versus 0 | 1.42 (0.87 to 2.31) | 1.24 (0.76 to 2.03) | 1.05 (0.74 to 1.50) | 0.99 (0.69 to 1.41) |
| 2 versus 0 | 1.91 (1.30 to 2.79)a | 1.56 (1.06 to 2.30)a | 1.10 (0.84 to 1.43) | 0.97 (0.74 to 1.27) |
| ≥3 versus 0 | 2.87 (2.0 to 4.12)a | 2.07 (1.43 to 3.01)a | 1.47 (1.14 to 1.90)a | 1.45 (1.11 to 1.90)a |
| Surgery year (versus 2001) | ||||
| 2002 | 1.49 (0.69 to 3.22) | 1.70 (0.78 to 3.68) | 1.08 (0.47 to 2.46) | 1.36 (0.59 to 3.12) |
| 2003 | 1.29 (0.61 to 2.72) | 1.26 (0.60 to 2.67) | 0.67 (0.28 to 1.59) | 0.62 (0.26 to 1.48) |
| 2004 | 1.21 (0.58 to 2.52) | 1.23 (0.59 to 2.57) | 0.45 (0.18 to 1.12) | 0.44 (0.17 to 1.12) |
| 2005 | 0.92 (0.44 to 1.93) | 1.05 (0.50 to 2.21) | 0.75 (0.34 to 1.64) | 0.76 (0.35 to 1.67) |
| 2006 | 1.28 (0.63 to 2.62) | 1.22 (0.59 to 2.49) | 1.07 (0.51 to 2.23) | 1.06 (0.50 to 2.22) |
| 2007 | 1.02 (0.49 to 2.13) | 1.24 (0.59 to 2.60) | 0.85 (0.41 to 1.77) | 0.87 (0.42 to 1.82) |
| 2008 | 0.94 (0.45 to 1.95) | 1.08 (0.52 to 2.26) | 0.99 (0.48 to 2.02) | 0.98 (0.48 to 2.02) |
| 2009 | 1.05 (0.51 to 2.17) | 1.70 (0.82 to 3.52) | 0.93 (0.46 to 1.91) | 0.92 (0.45 to 1.89) |
| 2010 | 0.69 (0.33 to 1.46) | 1.18 (0.55 to 2.51) | 0.82 (0.40 to 1.66) | 0.83 (0.41 to 1.69) |
| 2011 | 0.68 (0.32 to 1.46) | 0.97 (0.45 to 2.09) | 0.98 (0.49 to 1.99) | 1.06 (0.52 to 2.14) |
| 2012 | 0.97 (0.47 to 2.01) | 1.61 (0.77 to 3.35) | 0.85 (0.42 to 1.74) | 0.96 (0.47 to 1.95) |
| 2013 | 1.30 (0.56 to 2.99) | 1.97 (0.85 to 4.55) | 1.45 (0.68 to 3.09) | 1.50 (0.70 to 3.20) |
HR, Hazard Ratio.
a
Hazard ratios met a statistical significance threshold of P<0.05.